Monocytes are bone marrow-derived leukocytes that circulate in the blood and spleen. Characterized by their ability to recognize “danger signals”, monocytes can phagocytose and present antigens, secrete chemokines, and proliferate in response to infection and injury. Once recruited to tissues, monocytes are capable of differentiating into macrophages and dendritic cells. Monocytes and macrophages are key components of the innate immune system and are involved in the regulation of the initiation, development, and resolution of many inflammatory disorders.
Moreover, these cells also play important immunoregulatory and tissue-repairing roles to decrease immune reactions and promote tissue regeneration. Furthermore, they also contribute to a broad spectrum of pathologies and are thus attractive therapeutic targets.
Creative Biolabs has developed a range of high-quality monocytes by positive or negative selection from different species and sources. When commercially available off-the-shelf (COTS) products are not enough, trust Creative Biolabs to develop a solution that will provide the best results you require. Please don't hesitate to contact us and see how we can help you with your project.
For Research Use Only. Do Not Use in Food Manufacturing or Medical Procedures (Diagnostics or Therapeutics). Do Not Use in Humans.