With an experienced team of in-house human and mouse macrophage characterization experts, Creative Biolabs has explored a comprehensive portfolio of strategies to provide our clients with highly customizable solutions. From project design to result analysis, our seasoned scientists will work with you to develop a complete solution for our client's needs in macrophage characterization.

Macrophage Characterization Services at Creative Biolabs

Macrophages are a heterogeneous cell population with high plasticity. The identity and function of macrophages can be influenced by resident tissue environment, exposure to activation signal and ontogeny. Previous studies have shed light on discrepancies between human and mouse macrophages. Moreover, the characterization of human macrophages may help their identification in different diseases and the development of innovative therapeutic approaches.

Creative Biolabs combines industry-leading expertise with an innovative platform to provide a full portfolio of high-quality macrophage characterization services, which focus on the difference analysis in morphology, phenotype, proliferation capability, phagocytosis capability, antigen presentation capability, and cytokine expression profile. Our customizable menu includes but is not limited to:

Morphological Difference Analysis

Creative Biolabs takes advantage of the Gimesa-Wright staining and lysosome staining to analyze the morphological difference among macrophages. This service is focused on offering staining techniques with enhanced dyes to deliver superior performance, aiding in morphological difference analysis among diverse macrophages.

Phenotype Difference Analysis

Creative Biolabs utilizes the method of flow cytometry to analyze phenotype differences among diverse macrophages. We provide multiple types of cytometry such as multicolor conventional flow cytometry, spectral flow cytometry, mass cytometry, and improved multicolor flow cytometry. Moreover, we also deliver several choices on fluorochromes in cytometry, aiming to satisfy customers' multiple demands.

Proliferative Capability Analysis

For the proliferative capability of macrophages, Creative Biolabs fusion employs a variety of proliferation approaches including cell metabolic activity analysis, DNA synthesis assay, ATP content detection, etc., to analyze macrophages from multiple dimensions.

Phagocytosis Capacity Analysis

To examine macrophages' phagocytosis, Creative Biolabs takes advantage of a FITC-dextran uptake assay featuring excellent fluorescence effect and biocompatibility. Moreover, this service is inclusively appropriate for diverse samples such as different tissue source macrophages and cell lines.

Antigen-presenting Capacity Assessment

To aid in macrophage therapeutic projects, Creative Biolabs integrates the gold standard thymidine incorporation assay into our macrophages' antigen-presenting capacity analysis. With simple steps and our seasoned research teams, we have great confidence in delivering high-quality antigen-presenting capacity analysis outcomes.

Cytokine Expression Profiling

Profiling cytokine expression patterns in macrophages offers valuable insights for studying their distinct characteristics. Accordingly, Creative Biolabs specifically delivers a sensitive and robust cytokine expression profile service incorporating real-time PCR assay or microarray assay for high-throughput analysis of the cytokine expression among macrophages.

Macrophage Characterization

Innovatively, Creative Biolabs incorporates the mass cytometry-based phagocytosis assay into our macrophage characterization services, which is able to achieve macrophage characterization at a single-cell level. In addition, this service possesses great potential in cellular biomarkers quantizing and cellular heterogeneity characterizing.

Single-Cell Mechanical Characterization

The single-cell mechanical characterization service from Creative Biolabs has great potency in studying the mechanical properties of macrophages. Furthermore, we have the ability to provide a wide range of well-equipped single-cell mechanical characterization approaches to support global customers' meaningful macrophage projects.

Related Products

In our macrophage characterization service, we can achieve phenotypic identification and functional assessment through a variety of technologies. In addition, we also provide the key product systems required for the corresponding experiments, including macrophage cells, culture and differentiation tools, and detection reagents.

Below are some of our popular products. You can click to view the details.

Service Features

Flexible Sample Processing Options

Supports single-cell suspension preparation of whole blood, tissue or tumor samples, compatible with PBMC isolation, monocyte differentiation and direct analysis processes. Adopt various separation techniques such as magnetic bead sorting and FACS to ensure the purity of target cells.

Highly Accurate Cell Analysis

Our service uses advanced flow cytometry and microimaging technologies to efficiently and accurately identify and analyze macrophage types, states and their functions. This ensures the reliability and reproducibility of the experimental results and helps customers get more accurate data support.

Customized Service Solutions

We understand that the needs of different clients vary and therefore offer flexible and customized services. Whether it is for basic research, preclinical studies or drug development, we can design an experimental protocol that is tailored to the specific needs to ensure that their research goals are met.

Professional Technical Support and Data Interpretation

Our team consists of experienced scientists and technicians who can not only provide technical support, but also provide in-depth analysis and interpretation of experimental data. We will provide our clients with detailed reports and consulting services.

Workflow of Macrophage Characterization Services

Scientific Resources

Learn More Macrophage Biology

Download M1 vs. M2 Macrophages

Learn More Methods for Evaluation of Macrophage Function In Vitro

Learn More Isolation and Identification of Macrophages

Q & A

Q: What types of samples can you process?

A: We can process many types of samples, including peripheral blood, bone marrow, spleen, lymph node and various tissue samples. Specific sample types and processing methods will be customized according to the client's needs and actual situation.

Q: What materials or information do I need to prepare for the service application?

A: You need to provide cell samples (e.g. blood or tissue samples), relevant research information as well as the purpose of the experiment and desired results. This will help us better understand your needs and customize a service plan for you.

Q: What will be included in the analysis and report of the experimental results?

A: The final lab report will present the experimental design, experimental methodology, result data (including graphs and images), statistical analysis, and our discussion and conclusions in detail. The report will clearly describe the characteristics of macrophages and their biological functions, and provide professional recommendations or directions for follow-up research.

Q: How is the price calculated and are there any extra charges?

A: Prices are usually calculated based on the complexity of the experimental project, the number of samples and the required analyses. We will provide a detailed quote before the service begins and ensure that the client follows the terms of the contract without incurring any additional costs. If additional services or analyses are required, the related costs will be explained after prior negotiation.