HL-60-based Macrophage Model Development Service

HL-60 cells serve as an invaluable tool for advancing our understanding of leukemia, hematopoiesis, and various other aspects of cell biology and disease pathology. Creative Biolabs has developed HL-60-based macrophage models, providing a valuable experimental system for elucidating the biology of macrophages and their role in health and disease, and a versatile platform for researchers to conduct mechanistic studies, drug screening assays, and translational research work.

HL-60 Cells

HL-60 cells are a type of human promyelocytic leukemia cell line commonly used in biomedical research, particularly in studies related to hematology, immunology, and cancer. These cells were originally isolated from the peripheral blood of a patient with acute promyelocytic leukemia (APL) in 1977.

HL-60-based Macrophage Model Development Service at Creative Biolabs

Creative Biolabs provides services for the development of HL-60-based macrophage models, including cell culture, cell differentiation, immunological assays, and data analysis. Creative Biolabs has experience in developing and validating such models to ensure their reliability and relevance for research or drug discovery purposes.

If you have any needs other than HL-60-based macrophage model development services, feel free to contact us our scientists!

Display Results

HL60 cells treated with different differentiation agents
Fig.1 Immunocytochemical staining of HL-60 cells. (Masuki, Hideo et al., 2022)
Fig.1 HL60 cells treated with different differentiation agents.1
The cells shown on the left were treated with silica MP for 3 days. The cells were then fixed and subjected to immunocytochemical CD11b staining, followed by DAPI staining, and the CD11b expression level of HL60 cells treated with PMA and DMSO was evaluated.

Frequently Asked Questions

Q1: Why choose the HL-60-based macrophage model?

A1: HL-60-based macrophage models offer several advantages in studying macrophage biology and related fields:


  1. Masuki, Hideo et al. "Responses of promyelocytic leukemia HL60 cells as an inflammatory cell lineage model to silica microparticles used to coat blood collection tubes." International journal of implant dentistry. (2022) 8,1 24.
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