Tissue-specific Macrophage Development Services

Macrophages are specialized immune cells that play a crucial role in the body's defense against pathogens and help maintain tissue homeostasis. They are a diverse group of cells with distinct functions and developmental pathways. Tissue-resident macrophages are found throughout the body and are involved in a variety of biological processes such as immune response, tissue repair, and metabolism. Creative Biolabs offers a comprehensive tissue-specific macrophage development service, supported by our knowledgeable team of scientists, for a wide range of research applications.

Fig.1 Tissue-specific macrophages. (Lee, et al., 2023) Fig.1 Macrophages from specific tissues.¹

Tissue-specific Macrophage Development Service at Creative Biolabs

Macrophages play a vital role in maintaining tissue balance and responding to injuries and infections throughout the body's lifespan. Our service has the potential to isolate and culture the macrophages from specific tissues such as bone, lung, CNS, etc. To better evaluate these macrophages, we provide a wide range of specific markers. Incorporating advanced technologies, our seasoned scientists are willing to help global customers engineer or analyze the desired macrophages to meet your multiple demands. Based on our robust macrophage therapeutic platform, we have great confidence in answering each of you with ideal results in a timely manner. Our tissue-specific macrophage development service menu involves:

Tissue-specific Macrophage Types & Markers

Creative Biolabs delivers a series of macrophages derived from distinctive tissues and specific markers for better analysis and research on these macrophages.

Tab.1 Tissue-specific macrophage types & markers.

Bone	CNS	Lung	Liver		Spleen			Adipose
osteoclasts	microglial cell	Alveolar macrophage	Kupffer cell	Motile liver macrophage	White-pulp macrophage	Red-pulp macrophage	Marginal-zone macrophage	Adipose tissue-associated macrophage
Markers: Calcitonin Receptor⁺, F4/80^low/−, RANK⁺, NFATc1⁺, Tartrate-resistant acid phosphatase (TRAP)⁺.	Markers: AIF-1/Iba1⁺, CD11b/Integrin αM⁺, CD45low, F4/80.	Markers: CD11b/Integrin αM^low/–, CD11c^high, CD68/SR-D1⁺, CD200 R1⁺, DEC–205/CD205int, Dectin-1⁺, F4/80^low, Galectin-3/Mac-2⁺, MARCO⁺, MHC class II^low, MMR/CD206^high, PPARg⁺, Siglec-F^high).	Markers: B7-1/CD80^low/–, CD11b/Integrin αM^low, CD68/SR-D1⁺, F4/80^high, Galectin-3/Mac-2⁺, PPARδ⁺, Siglec-1/CD169⁺.	Markers: B7-1/CD80^high, CD11b/Integrin αM⁺, F4/80.	Markers: CD68/SR-D1⁺, MFG-E8⁺, MerTK⁺, TIM-4⁺.	Markers: CD11b/Integrin αM^low, CD36/SR-B3⁺, CD68/SR-D1⁺, CD163⁺, Dectin-2⁺, F4/80⁺, MMR/CD206⁺, SIRPa/CD172a⁺, Spi-C⁺, VCAM-1/CD106⁺.	Markers: CD68/SR-D1⁺, Dectin-2⁺, F4/80^low, LXRa/NR1H3⁺, MARCO⁺, SIGNR1/CD209b⁺, TIM-4⁺.	Markers: CD45⁺, F4/80⁺, PPARγ⁺.

Advantages of Our Tissue-specific Macrophage Development Service

Excellent Stability.
Proven Technologies.
Strict quality control.
Ph.D. research team.
One-stop customized service.

Frequently Asked Question

Q1: What is the project process of the tissue-specific macrophage development service?

A1: Firstly, you need to tell us your demands on tissue-specific macrophage development. After, our scientific team discusses your project and makes a proposal. When you receive our proposal, you need to consider it and answer us. We improve your project scheme and run it. For special projects, please contact our team of experts directly to help you.

As a leader in macrophage research, Creative Biolabs is constantly bringing out more meaningful service. If you want to know more information about our tissue-specific macrophage development service, please contact us without hesitation.

Reference

Lee, Min-Kyeong, et al. "The role of macrophage populations in skeletal muscle insulin sensitivity: Current understanding and implications." International Journal of Molecular Sciences 24.14 (2023): 11467.