Macrophage-targeted Dendrimer Drug Delivery System

Equipped with state-of-the-art facilities and experienced immunology experts, Creative Biolabs has expanded its service capabilities to offer an integrated solution for macrophage-targeted dendrimer drug delivery system development service to facilitate your project success.

Introduction of Macrophage-targeted Dendrimer Drug Delivery System

Dendrimers are a kind of emerging polymeric materials with three-dimension, immense branch, and well-structure. Which have several characteristics, such as well chemically stability, high water solubility, biocompatibility, polyvalency, and less cytotoxicity. These features make them an ideal carrier for drug delivery and targeting applications. Many studies have been targeted on dendrimers to discover their potential for targeted drug delivery.

Illustration of various dendron-polymer conjugates assembling to form nano-sized drug delivery vehicles. Fig.1 Illustration of various dendron-polymer conjugates assembling to form nano-sized drug delivery vehicles. (Bolu, 2018)

As a vital cell type, macrophages are distributed to act against pathogens and foreign particles and play an important role in the maintenance of homeostasis. More importantly, macrophages have been widely used in the development of drug delivery systems, due to the many advantages, such as prolonging the circulation and release of drugs, extending the half-life, improving their stability, and reducing immunogenicity. Thus, macrophages-targeted drug delivery systems as a promising solution in the field of diseases.

Working with Creative Biolabs

Creative Biolabs is a world-leading services provider in the field of macrophage-targeted drug delivery system development. With profound expertise and state-of-the-art technology platforms, we are committed to providing tailored solutions for macrophage-targeted dendrimer drug delivery system development to each project to ensure that the objectives are met or exceeded. If you are interested in our services, please contact us to discuss your project.

References

  1. Bolu, B.S.; et al. Drug delivery systems from self-assembly of dendron-polymer conjugates. Molecules. 2018, 23(7), 1570.
  2. Mehta, M.; et al. Interactions with the macrophages: an emerging targeted approach using novel drug delivery systems in respiratory diseases. Chemico-biological interactions. 2019, 304, 10.
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