KG-1-based Macrophage Model Development Service

KG-1 cells are commonly used in research as a model system for studying myeloid differentiation, leukemia biology, and the effects of various compounds on myeloid cell growth and differentiation. KG-1 cells have been particularly useful in investigations related to hematopoiesis, leukemia pathogenesis, and drug screening studies. Creative Biolabs develops a macrophage model based on KG-1 cells, which consists of culturing and inducing differentiation into macrophage-like cells.

KG-1 Cells

KG-1 cells are a human myeloblastic leukemia cell line derived from the peripheral blood of a patient with acute myelogenous leukemia (AML). KG-1 cells are characterized by their ability to differentiate into mature myeloid cells, including granulocytes, monocytes, and macrophages, under appropriate culture conditions.

Key characteristics of KG-1 cells include their suspension growth in culture, relatively low proliferation rate, and responsiveness to differentiation-inducing agents such as phorbol esters (e.g., phorbol 12-myristate 13-acetate, PMA) and vitamin D3. They are often utilized as a tool for understanding the mechanisms underlying myeloid differentiation and for screening potential therapies targeting leukemia or myeloid disorders.

Fig.1 KG-1 cells in culture flask.1

KG-1-based Macrophage Model Development Service at Creative Biolabs

Fig.1 KG-1 cells. (Shaban Alizadeh.; et al., 2009)

Creative Biolabs has expertise in cell culture, differentiation protocols, immunological assays, and data analysis. When providing macrophage model development services for KG-1, models can also be customized to meet your specific research needs and goals.

Frequently Asked Questions

Q1: Why choose the KG-1-based macrophage model?

A1: Choosing a KG-1-based macrophage model over other options like HL-60 or THP-1 cells depends on the specific research needs and goals.

Creative Biolabs has always put the needs of our customers first, and if you have any questions about the KG-1 macrophage model, you can contact us directly for assistance.


  1. Shaban Alizadeh.; et al. "Antineoplastic effect of fenugreek (trigonella foenum graecum) seed extract against acute myeloblastic leukemia cell line (KG-1)." Iranian Journal of Blood and Cancer. (2009) 1(4): 139-146
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