Atherosclerotic cardiovascular disease is a chronic condition characterized by the buildup of plaque in the arteries, leading to inflammation and narrowing of the blood vessels. Macrophages play a key role in this process, as they are responsible for promoting inflammation within the plaque. Smooth muscle cells also contribute to the development of atherosclerosis by proliferating and forming a fibrous cap over the plaque. Based on our innovative platform, Creative Biolabs offers a dependable coculture system that allows for the study of the interaction between macrophages and smooth muscle cells in atherosclerosis research.

Fig.1 The interactions between macrophages and vascular smooth muscle cells (VSMCs) in atherosclerosis.¹

Macrophage-Smooth Muscle Cell Coculture Model Development Service at Creative Biolabs

Our macrophage-smooth muscle cell co-culture model development service is backed by extensive expertise and experience in cell biology and model development. Through the interaction of macrophages and smooth muscle cells in our co-culture model, we aim to replicate the in vivo environment and understand the mechanisms of these two cell types. By establishing direct contact cultures or utilizing transwell devices, we have great capacity to create models that mimic the physiological interaction between macrophages and smooth muscle cells. Different cultural methods have specific applicable research scope. We are able to customize your experiment scheme to meet your unique requirements. Creative Biolabs is a reliable partner to work together for the development of macrophage-smooth muscle cell coculture model models with good performance.

Fig.2 Simple diagram of our coculturing strategies.

Advantages of Our Macrophage-Smooth Muscle Cell Coculture Model Development Service

• Our macrophage-smooth muscle cell co-culture model development is applicable to multiple species.
• Comprehensive analysis from morphological to molecular changes to evaluate your therapeutics.
• Our expert team supervises the whole process to guarantee the smooth operation of your project.
• High-quality results delivery and after-sale support boost your project move to the clinical stage.

Potential Applications

• Our macrophage-smooth muscle cell coculture model is versatile and effective for investigating different biological phenomena, such as cell-cell interactions, signal transduction pathways, cellular migration, and drug screening applications.
• Our macrophage-smooth muscle cell coculture model is extensively utilized in research for drug testing, treatment efficacy assessment, and therapeutic discovery.
• Our macrophage-smooth muscle cell coculture model is also helpful for evaluating the biomaterials used to repair or replace diseased blood vessels.

With a strong foundation in cell biology and model construction, Creative Biolabs stands at the forefront of innovation in developing macrophage-smooth muscle cell co-culture models. Drawing from a rich tapestry of experience and expertise, our team is committed to delivering customized solutions that meet our customers' specific requirements. If you are looking to delve deeper into the information of macrophage-smooth muscle cell coculture models, we invite you to get in touch with us for comprehensive insights and information.