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Liver Capsular Macrophages (LCMs), Liver (MT-0224-HM11)

Datasheet

Overview

Description

Liver Capsular Macrophages (LCMs) are a specialized subset of macrophages located within the liver capsule, specifically in the subcapsular region. They are distinct from Kupffer cells, which are predominantly found within the liver sinusoids.

Applications

Numerous types of experimental manipulations, including morphological, gene expression, and physiological studies.

Species

Mouse

Original

Monocytes

Product Type

Tissue-specific Macrophages

Specification

Cell Source

Liver

Status

Frozen

Formulation

Cryopreservation medium

Quality Control

Cells are negative for mycoplasma, bacteria, fungi and yeast.

Medium

Recommended medium

Shipping Info

Dry ice

Size

1×10⁶ cells

Handling Notes

Upon receiving, transfer this product directly from dry ice to liquid nitrogen(-150°C~-190°C) and store it in a liquid nitrogen tank.
We cannot guarantee the cell viability if the cells are not treated appropriately according to handling procedure.

Storage

Avoid repeated freezing & thawing.

Product Disclaimer

Product Disclaimer

This product is provided for research only, not suitable for human or animal use.
We ensure the safety of our products, but we still recommend handling any biological materials with standard precautions as if able to spread infectious disease.

FAQs Customer Reviews Related Products

How do you validate the identity of your liver capsular macrophages?

We perform flow cytometry for CD11b, F4/80, and MHC-II, assess morphology, and test cytokine responsiveness. This ensures authenticity and suitability for immune-microenvironment studies.

Can these macrophages be incorporated into ECM-based liver models?

Yes. LCMs adhere well to biological or synthetic scaffolds, retaining functional responsiveness that supports microenvironment modeling for infection, inflammation, or biomaterial testing.

What documentation accompanies each LCM shipment?

We include QC data covering purity, identity, viability, morphology, and cytokine-response behavior, enabling researchers to evaluate lot suitability before integrating the cells into specialized liver models.

These liver capsular macrophages performed exceptionally well in our capsular fibrosis model
Their responses to matrix stiffness and mechanical stimulation produced valuable mechanobiological insights we previously couldn't capture.
Their cytokine profiles remained consistent across replicates
The cells demonstrated strong viability and stability in culture, which helped us run longer-term stimulation studies.
What stood out was how well they retained their capsular identity
This made our peritoneal-liver crosstalk experiments far more physiologically relevant and generated clearer mechanistic data.

For Research Use Only. Do Not Use in Food Manufacturing or Medical Procedures (Diagnostics or Therapeutics). Do Not Use in Humans.