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Intraventricular Macrophages, Central Nervous System (MT-0224-HM5)

Datasheet

Overview

Description

Intraventricular macrophages, also known as ventricular macrophages, are a specialized population of immune cells found within the ventricular system of the brain. These macrophages play crucial roles in maintaining homeostasis, immune surveillance, and response to pathological conditions within the central nervous system (CNS).

Applications

Numerous types of experimental manipulations, including morphological, gene expression, and physiological studies.

Species

Mouse

Original

Embryonic Progenitors

Product Type

Tissue-specific Macrophages

Specification

Cell Source

Central Nervous System

Status

Frozen

Formulation

Cryopreservation medium

Quality Control

Cells are negative for mycoplasma, bacteria, fungi and yeast.

Medium

Recommended medium

Shipping Info

Dry ice

Size

1×10⁶ cells

Handling Notes

Upon receiving, transfer this product directly from dry ice to liquid nitrogen(-150°C~-190°C) and store it in a liquid nitrogen tank.
We cannot guarantee the cell viability if the cells are not treated appropriately according to handling procedure.

Storage

Avoid repeated freezing & thawing.

Product Disclaimer

Product Disclaimer

This product is provided for research only, not suitable for human or animal use.
We ensure the safety of our products, but we still recommend handling any biological materials with standard precautions as if able to spread infectious disease.

FAQs Customer Reviews Related Products

Are these macrophages suitable for modeling early immune responses to CSF-borne pathogens?

Yes. Their preserved innate-sensing capability supports realistic studies on pathogen recognition, antiviral signaling, and cytokine induction within ventricular environments. They are highly relevant for infection models that require accurate simulation of CSF-exposed immune sentinels.

What identity markers do you verify to confirm intraventricular macrophage authenticity?

We assess CSF-interface markers, innate-sensing receptors, morphology, and viability. Cytokine-response assays further validate functional identity, ensuring high relevance for studies involving immune signaling along ventricular surfaces.

Can these cells adapt to microfluidic devices simulating CSF pulsation?

Yes. We confirm that the cells maintain morphology and inflammatory responsiveness under pulsatile flow. Their stability under dynamic conditions makes them ideal for modeling CSF-driven immune signaling and ventricular barrier interactions.

These intraventricular macrophages worked extremely well in our CSF-flow microfluidic platform
Their migratory behavior, responsiveness to chemotactic gradients, and overall viability closely resembled physiological conditions. They enabled us to model ventricular immune surveillance with much higher fidelity.
We were impressed by the cells' robustness and consistency after thawing
They stabilized quickly and interacted naturally with our ventricular epithelial cells. Cytokine responses to stimulation were strong but not exaggerated, providing clean datasets for downstream analysis.
These macrophages dramatically improved the realism of our ventricular inflammation model
Their sensitivity to soluble factors and motility under controlled flow conditions allowed us to map immune gradients in ways that were not possible before.

For Research Use Only. Do Not Use in Food Manufacturing or Medical Procedures (Diagnostics or Therapeutics). Do Not Use in Humans.