Yes, as primary bone marrow-derived macrophages, these cells represent a naïve (M0) population that is fully capable of being polarized in vitro to M1 or M2 phenotypes using standard cytokine cocktails.
They are ideal for studies where a hamster model is required, such as research on COVID-19 (as hamsters are a susceptible model), leishmaniasis, or other metabolic and infectious diseases. They are suitable for phagocytosis, cytokine release, and gene expression assays.
To ensure maximum viability, you must immediately transfer the frozen vial from the dry ice shipping container to a liquid nitrogen tank (-150°C to -190°C) for long-term storage. Do not store at -80°C.
For Research Use Only. Do Not Use in Food Manufacturing or Medical Procedures (Diagnostics or Therapeutics). Do Not Use in Humans.