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Balb/C Mouse Macrophages, Peripheral Blood,>5 x 10^6 (MTS-0922-JF33)

Datasheet

Overview

Description

This product is isolated from the peripheral blood of pathogen-free laboratory Balb/C mouse.>5 x 10^6 cells are delivered frozen. This product is negative in the tests of mycoplasma, bacteria, fungi and yeast. The expression of CD11b is positive by flow cytometry. It is guaranteed to further culture in the conditions provided by Creative Biolabs. Repeated freezing and thawing of cells is not recommended.

Applications

Numerous types of experimental manipulations, including morphological, gene expression, and physiological studies.

Species

Mouse

Product Type

Balb/C Mouse Macrophages

Specification

Cell Source

Peripheral blood

Marker expression

Expressed on macrophages, CD11b plays a critical role in regulating pathogen recognition, phagocytosis, and cell survival. The expression of CD11b is positive by flow cytometry.

Status

Frozen

Formulation

Cryopreservation medium

Quality Control

Cells are negative for mycoplasma, bacteria, fungi and yeast.

Medium

Recommended medium

Shipping Info

Dry ice

Size

>5 x 10^6 cells

Handling Notes

Upon receiving, transfer this product directly from dry ice to liquid nitrogen(-150°C~-190°C) and store it in a liquid nitrogen tank.
We cannot guarantee the cell viability if the cells are not treated appropriately according to handling procedure.

Notes

Avoid repeated freezing & thawing.

Product Disclaimer

Product Disclaimer

This product is provided for research only, not suitable for human or animal use.
We ensure the safety of our products, but we still recommend handling any biological materials with standard precautions as if able to spread infectious disease.

FAQs Customer Reviews Related Products

What is the difference between these peripheral blood-derived macrophages and your bone marrow-derived (BMDM) ones?

The main difference is the source of the precursor cell. These cells are differentiated in vitro from monocytes isolated from peripheral blood (PBMCs), whereas BMDMs are differentiated from bone marrow precursors. They are both M0 macrophages but may have subtle functional differences, making them two distinct models.

Why would I choose peripheral blood-derived macrophages?

This model is an excellent representation of circulating monocytes that are recruited to a site of inflammation and then differentiate into macrophages. This makes them a more relevant model for studying acute inflammatory processes or diseases where monocyte recruitment is a key factor.

What is the significance of the BALB/c strain?

The BALB/c strain is Th2-biased. You should choose these cells if your research is focused on Th2-driven diseases, such as allergy, asthma, or parasitic infections, and you want to model the role of blood-recruited monocytes in that context.

High viability and a very healthy-looking population
Good, clean cells. They polarized to M2 very well with IL-4. The protocol was easy to follow. We are happy with the results.
The 5 million count is a good value
An interesting model. They behave slightly differently than BMDMs, which was important for our publication. The 5M cell count is great. A solid product.

For Research Use Only. Do Not Use in Food Manufacturing or Medical Procedures (Diagnostics or Therapeutics). Do Not Use in Humans.