Microglia and other macrophages play a vital role in the central nervous system by safeguarding its health, ensuring proper functioning, and promoting stability. However, under pathological conditions, microglia and macrophages may become overactivated and release excessive inflammatory mediators, leading to neuronal death and tissue damage. Therefore, in-depth analysis of the pathological functions of CNS microglia and macrophages will help to understand their role in the occurrence and development of CNS diseases, and thus provide clues for finding new therapeutic strategies. Creative Biolabs specializes in providing the pathological function analysis service to get more insights on CNS microglia and macrophages for effective therapeutics development.

Fig.1 Multiple functions of microglia and macrophages in brain injury.¹

Pathological Function Analysis of CNS Microglia and Macrophages at Creative Biolabs

The pathological function analysis of CNS microglia and macrophages provided by Creative Biolabs incorporates expertise in molecular biology, cell biology, bioinformatics, etc., which is beneficial for multi-dimensional pathological function analysis.

Under pathological conditions, CNS microglia and macrophages are overactivated and release a variety of cytokines, leading to the presence of a variety of heterogeneous cell populations. Compared with normal cells, their metabolic processes and phagocytosis are disrupted, resulting in neuronal death and tissue damage.

According to that, we provide a series of function analyses as follows to comprehensively understand the CNS microglia and macrophages under pathological. To identify the distinctive heterogeneous populations, we provide a reliable and effective marker development service for global customers. In addition, we also provide numerous well-developed analysis technologies to strengthen our pathological function analysis service of CNS microglia and macrophages. Collectively, Creative Biolabs is willing to work closely with you to present desirable analysis results to aid in your CNS microglia and macrophage projects.

Potential Therapeutic Strategies Targeting CNS Microglia and Macrophages

• Inhibiting the pro-inflammatory response of microglia/macrophages.
• Improving the neuroprotective activity of microglia and macrophages.
• Regulating metabolism of microglia/macrophages.

Features of Our Pathological Function Analysis of CNS Microglia and Macrophages

• Comprehensive analysis.
• Selective analysis technologies.
• Seasoned scientist team.
• Strict quality control.
• Reliable after-sales service

As an industrial leader in tissue-specific macrophage analysis, Creative Biolabs is constantly improving the current technology analysis and developing more effective and time-saving services to assist global customers in the development of therapeutic compounds and approaches. If you are seeking a reliable partner who can assist you in progressing your CNS microglia and macrophage analysis initiatives, please contact us without delay.