Tissue macrophages are supportive cells embedded in most tissues at minute percentages (1-5%), playing a critical role in maintaining stability during organ formation, tissue reconstruction, and metabolic modification. They are essential actors in the immune response of both ordinary and tumoral tissues, which triggers numerous research interests in therapeutic development. Electron Microscopy serves as a vital tool in examining the minute intracellular structures of macrophages and other cells. Creative Biolabs offers an extensive electron microscopy analysis service for tissue-specific macrophages exploiting this technology. Together with our competent research team, we will strive to analyze tissue-specific macrophages throughout for a better understanding of them.

Fig.1 Fetal growth of Macrophages.¹

Electron Microscopy Analysis of Tissue-specific Macrophages at Creative Biolabs

Creative Biolabs' electron microscopy analysis of tissue-specific incorporates the advantages of electron microscopy, which is able to observe the details of these cells in their physiological state with extremely high resolution. We provide complete sample preparation services to ensure the smooth progress of the entire process, including sample dilution, dehydration, embedding, sectioning, and staining.

With the use of our electron microscopy analysis service, customers are capable of observing the detailed morphology of tissue-specific macrophages under the ultrastructure, which helps understand the biological characteristics and functions of these macrophages. At the same time, customers are able to obtain the kinetic imaging of the phagocytosis of microorganisms and tumor cells by macrophages, as well as the synthesis and decomposition of various biomolecules in these cells. Furthermore, electron microscopy analysis of tissue-specific macrophages has the ability to facilitate mechanistic studies of interactions between these cells and other cells. Backed up by our robust macrophage development platform, we have great confidence in encouraging global customers to inquire and place orders for your meaningful projects.

• Analytical electron microscope (AEM)
• Transmission electron microscope (TEM)
• Reflection electron microscopy (REM)
• Scanning electron microscopy (AEM)

Frequently Asked Questions

Q1: How to recognize macrophages under a microscope?

A1: Macrophage monocytes and eosinophils were distinguished via light, phase contrast, and electron microscopy. Additionally, the strong positive response to α-naphthyl acetate esterase reinforced the identification of macrophage monocytes, while the eosinophils were further identified through their affirmative stain using Luxol Fast Blue, eosin, and peroxidase.

Q2: What are the requirements for samples in electron microscopy analysis of tissue-specific macrophages?

A2: We need the customers to provide a sufficient number of cell samples to meet dilution requirements. Because the cell sample used for electron microscope analysis needs appropriate cell concentration, the sample can't be found if the cell concentration is too low, and if the cell concentration is too high, it is easy to agglomerate and the monomer structure can't be seen. For special projects, please contact our team of experts directly to help you.

For more details about our electron microscopy analysis of tissue-specific macrophages, please reach out to us in your free time.