CCR2 & Macrophage

CCR2, also known as CC chemokine receptor type 2, is a receptor protein found on the surface of immune cells including macrophages. Chemokine receptors like CCR2 play crucial roles in guiding immune cells to sites of inflammation or infection in the body.

Fig.1 CCR2+ macrophages in specific diseases.¹

CCR2 is particularly significant in the recruitment of monocytes, which are precursor cells to macrophages, to sites of inflammation. When certain chemokines bind to CCR2, it triggers a signaling cascade that attracts monocytes to the inflamed tissue. Once recruited, monocytes can then differentiate into macrophages, which contribute to the immune response by phagocytosing pathogens, producing inflammatory mediators, and facilitating tissue repair. The interaction between CCR2 and macrophages plays a crucial role in orchestrating the immune response to infection, inflammation, and tissue damage. Dysfunction in this interaction can contribute to various inflammatory diseases and conditions. Creative Biolabs offers tissue-specific macrophage-blocking services based on CCR2 knockout to help you accelerate your specific research on macrophages.

Our CCR2 Knockout-based Tissue-specific Macrophage Blocking Service

The interaction between CCR2 and macrophages plays a crucial role in orchestrating the immune response to infection, inflammation, and tissue damage. Dysfunction in this interaction can contribute to various inflammatory diseases and conditions. Creative Biolabs is committed to creating a comprehensive one-stop macrophage blockade service platform, we provide but are not limited to the following services. If you have any other special customization requirements, you can contact us directly.

• Specific animal model
• Flow cytometry
• Cardiac MRI
• Ambulatory ECG telemetry
• Bone marrow transplantation
• CCR2+ macrophage density analysis
• Real-time qPCR
• scRNA-seq
• Differential expression and gene set enrichment analyses

For more Tissue-specific Macrophage Blocking Services, please click here!

As a leading provider in the field of macrophage R&D, Creative Biolabs provides you with one-stop macrophage services, including cell culture, characterization, reprogramming, engineering, etc. If you're interested, you can click on keywords for more information.