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MacroCargo™ Human THP-1 with Oncolytic virus (Co-culture System) (MTS-1122-YF248)

Name: MacroCargo™ Human THP-1 with Oncolytic virus (Co-culture System)
SKU: MTS-1122-YF248
Rating: 5 (1 reviews)

Datasheet

Cell Properties

Product Overview

As a therapeutic tool, macrophage cell has a great capacity for delivering cargos because of their intrinsic characteristics. This product is engineered Human THP-1 carried with Oncolytic virus by Co-culture System. MacroCargo™ products aim to improve the macrophage function and delivery of specific cargos. We also provide custom macrophage delivery systems based on your specific requirements.

Cell Name

THP-1

Cell Type

Cell Line

Cell Species

Human

Cell Background

THP-1 is a monocyte isolated from peripheral blood from an acute monocytic leukemia patient. This cell line can be used in immune system disorder research, immunology research, and toxicology research.

Cargo Properties

Cargo Type

Oncolytic virus

Specific Cargo

Oncolytic virus

Introduction

Oncolytic viruses provide direct cancer cell lysis, stimulate systemic immune responses, and have the capacity to provide therapeutic transgenes. Oncolytic virotherapy has shown great promise in many preclinical solid tumor models and the first oncolytic virus has been approved by the FDA for the treatment of advanced melanoma. As monotherapies for solid tumors, oncolytic virotherapy provides only moderate anti-tumor effects.The specific oncolytic virus will be determined according to specific requirements.

Cargo Delivery System Type

Co-culture System

Product Properties

Applications

Treatment for multiple cancers

References

Kono, Yusuke, et al. "Enhanced macrophage delivery to the colon using magnetic lipoplexes with a magnetic field." Drug Delivery 26.1 (2019): 935-943. Distributed under Open Access license CC BY 4.0, without modification.

Mycoplasma Testing

Negative

Sterility Testing

Negative

Shipping

Dry ice

Storage

Frozen cells should be stored in a liquid nitrogen tank (-150°C~-190°C) for long term.

Handling Notes

Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance.
Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line.
Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.

Restriction

Research use only