Akt Phosphorylation Assessment Service

Akt (Protein kinase B) serves as a critical regulator at the intersection of cell survival and death, exerting significant influence over cellular signaling pathways associated with metabolism, cell growth, apoptosis inhibition, and the formation of new blood vessels. When activated by phosphorylation, Akt triggers a cascade of events that support cell survival, proliferation, movement, and invasion, contributing to various essential biological functions. In order to better understand the role and mechanism of Akt in these physiological activities, Creative Biolabs provides an Akt phosphorylation assessment service to gain insight into its activation state and downstream effects under different environments and stimuli.

Fig.1 Akt’s role in AD. (Yang, et al., 2022)Fig.1 Akt in Alzheimer's disease.1

Akt Phosphorylation Assessment Service at Creative Biolabs

Creative Biolabs' Akt phosphorylation assessment service leverages our wealth of expertise in cell biology, supplying global customers with an effective pathway to insight into the Akt phosphorylation mechanism under various conditions. Our service is compatible with cell samples and tissue samples. Our matured therapeutic development platform offers a variety of state-of-the-art technologies. Noteworthy, these technologies have both benefits and cons. As a result, our experts provide help in selecting the optimal technology in accordance with your specific requirements and assessment strategies.

In addition, we also provide cell isolation or culture service, as well as tissue extraction service for subsequent analysis. Importantly, throughout the process, we need customers to provide candidate compounds to be tested. Our competent research team will present each of you with desirable findings about your compounds' effectiveness and efficacy on Akt phosphorylation.

Assessment Technologies at Creative Biolabs

At Creative Biolabs, we deliver a series of well-developed technologies featured with distinctive characteristics, including but not limited to the following:

Tab.1 Multiple assessment technologies at Creative Biolabs.

Technologies Features
Western blot High sensitivity; High specificity; Easy to operate
More samples and antibodies are required
Immunofluorescence
Immunoprecipitation
Mass spectrometry analysis High throughput; High sensitivity; High resolution; Multiple samples can be detected simultaneously
Flow cytometry High throughput; Multiple parameters can be analyzed simultaneously; Suitable for large sample analysis.
Fluorescent probe High sensitivity; High specificity; Easy to operate

Key Advantages

Potential Applications

Frequently Asked Question

Q: What are the special requirements for this service?

A: Our service is appropriate for cell samples and tissue samples. We need customers to provide your samples treated well. Noteworthy, If the treatment is not appropriate, it will affect the quality of the sample and ultimately affect the assessment results. So, we advise customers to select the optimal treatment and our experts are willing to help you with their expertise and experience. For the assessment of therapeutic compounds on Akt phosphorylation, we need customers to provide these compounds' basic information: testing samples, molecular weight, concentration, etc. For special projects, please contact our team to get specialized support.

For more details about our Akt phosphorylation assessment service, please don't hesitate to reach out to us.

Reference

  1. Yang, Shaobin, et al. "Reducing PDK1/Akt activity: an effective therapeutic target in the treatment of Alzheimer's disease." Cells 11.11 (2022): 1735.
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