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SIGLEC9 gRNA Lentiviral Particle for Macrophage Engineering (MTS-0124-LX34)

Datasheet

Overview

Description

The pre-made SIGLEC9 gRNA Lentiviral Particle is packaged using 3rd generation of lentiviral packaging system, serving as a convenient tool to support macrophage cell engineering.

Product Type

Virus Particles

Application Scenario

For in vivo and in vitro macrophage engineering

Target Specification

Engineering Approach

Target KO gRNA Contruction Lentivirus

Species

Human

Target

SIGLEC9 gRNA

Alternative Names

CD329; CDw329; FOAP-9; siglec-9; OBBP-LIKE

Full Name

Sialic acid binding Ig like lectin 9

Introduction

Predicted to enable monosaccharide binding activity and sialic acid binding activity. Predicted to be involved in cell adhesion. Predicted to act upstream of or within negative regulation of inflammatory response and negative regulation of phagocytosis, engulfment. Predicted to be located in external side of plasma membrane. Predicted to be active in plasma membrane.

UniprotID

Q9Y336

GeneID

27180

Applications

Promote the macrophage capability of limiting tumor growth

Reference

Mantovani, Alberto et al. "Macrophages as tools and targets in cancer therapy." Nature reviews. Drug discovery vol. 21,11 (2022): 799-820. doi:10.1038/s41573-022-00520-5

Product Specification

Packaging System

Lentivirus

Titer

>1E8 TU/mL

Size

200uL; 1mL

Mycoplasma Testing

Negative

Sterility Testing

Negative

Shipping

Dry ice

Storage

Stored at -80°C for long term.

Handling Notes

Avoid multiple freeze/thaw cycles.

Restriction

RUO

For Research Use Only. Do Not Use in Food Manufacturing or Medical Procedures (Diagnostics or Therapeutics). Do Not Use in Humans.