Engineering Approach
Target KO gRNA Contruction Lentivirus
Alternative Names
CD329; CDw329; FOAP-9; siglec-9; OBBP-LIKE
Full Name
Sialic acid binding Ig like lectin 9
Introduction
Predicted to enable monosaccharide binding activity and sialic acid binding activity. Predicted to be involved in cell adhesion. Predicted to act upstream of or within negative regulation of inflammatory response and negative regulation of phagocytosis, engulfment. Predicted to be located in external side of plasma membrane. Predicted to be active in plasma membrane.
Applications
Promote the macrophage capability of limiting tumor growth
Reference
Mantovani, Alberto et al. "Macrophages as tools and targets in cancer therapy." Nature reviews. Drug discovery vol. 21,11 (2022): 799-820. doi:10.1038/s41573-022-00520-5
Datasheet