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SIGLEC7 gRNA Lentiviral Particle for Macrophage Engineering (MTS-0124-LX33)

Datasheet

Overview

Description

The pre-packaged SIGLEC7 gRNA Lentiviral Particle as a convenient tool to aid in the research of macrophage cell engineering.

Product Type

Virus Particles

Application Scenario

For in vivo and in vitro macrophage engineering

Target Specification

Engineering Approach

Target KO gRNA Contruction Lentivirus

Species

Human

Target

SIGLEC7 gRNA

Alternative Names

p75; QA79; AIRM1; CD328; AIRM-1; CDw328; D-siglec; SIGLEC-7; SIGLECP2; SIGLEC19P; p75/AIRM1

Full Name

Sialic acid binding Ig like lectin 7

Introduction

Predicted to enable sialic acid binding activity. Predicted to be involved in cell adhesion. Predicted to be integral component of plasma membrane. Predicted to be active in plasma membrane.

UniprotID

Q9Y286

GeneID

27036

Applications

Promote the macrophage capability of limiting tumor growth

Reference

Mantovani, Alberto et al. "Macrophages as tools and targets in cancer therapy." Nature reviews. Drug discovery vol. 21,11 (2022): 799-820. doi:10.1038/s41573-022-00520-5

Product Specification

Packaging System

Lentivirus

Titer

>1E8 TU/mL

Size

200uL; 1mL

Mycoplasma Testing

Negative

Sterility Testing

Negative

Shipping

Dry ice

Storage

Stored at -80°C for long term.

Handling Notes

Avoid multiple freeze/thaw cycles.

Restriction

RUO

For Research Use Only. Do Not Use in Food Manufacturing or Medical Procedures (Diagnostics or Therapeutics). Do Not Use in Humans.