Online Inquiry

MacroCargo™ Mouse Bone Marrow-derived Macrophages (BMDM) with Chemo drugs (Nanoparticle System, PLGA) (MTS-1122-YF81)

Datasheet

Cell Properties

Product Overview

As a therapeutic tool, macrophage cell has a great capacity for delivering cargos because of their intrinsic characteristics. This product is engineered Mouse Bone Marrow-derived Macrophages (BMDM) carried with Chemo drugs by Nanoparticle System-PLGA. MacroCargo™ products aim to improve the macrophage function and delivery of specific cargos. We also provide custom macrophage delivery systems based on your specific requirements.

Cell Name

Bone Marrow-derived Macrophages (BMDM)

Cell Type

Primary Cell

Cell Species

Mouse

Cell Background

The broad use of transgenic and gene-targeted mice has established bone marrow-derived macrophages (BMDM) as important mammalian host cells for investigation of the macrophages biology.

Cargo Properties

Cargo Type

Chemo drugs

Specific Cargo

Chemo drugs

Introduction

To be determined according to specific requirements

Cargo Delivery System Type

Nanoparticle System

Cargo Delivery Approach

PLGA

Nanoparticle Component

Poly (lactic-co-glycolic acid)

Product Properties

Applications

Enhance chemotherapeutic drugs delivery to tumor; Reduce side effects

References

Allavena, Paola et al. "PLGA Based Nanoparticles for the Monocyte-Mediated Anti-Tumor Drug Delivery System." Journal of biomedical nanotechnology vol. 16,2 (2020): 212-223. doi:10.1166/jbn.2020.2881

Mycoplasma Testing

Negative

Sterility Testing

Negative

Shipping

Dry ice

Storage

Frozen cells should be stored in a liquid nitrogen tank (-150°C~-190°C) for long term.

Handling Notes

Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance.
Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line.
Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.

Restriction

Research use only