As a therapeutic tool, macrophage cell has a great capacity for delivering cargos because of their intrinsic characteristics. This product is engineered Mouse Ana-1 carried with Anti-SIGLEC10 antibody by Viral System-Lentivirus. MacroCargo™ products aim to improve the macrophage function and delivery of specific cargos. We also provide custom macrophage delivery systems based on your specific requirements.
Cell Name
Ana-1
Cell Type
Cell Line
Cell Species
Mouse
Cell Background
Ana-1 is a macrophage cell line, isolated from mouse thymus.
Cargo Properties
Cargo Type
Checkpoint antibody
Specific Cargo
Anti-SIGLEC10 antibody
Target Common Name
SIGLEC10
Target Alternative Names
SLG2; PRO940; SIGLEC-10
Target Full Name
Sialic acid binding Ig like lectin 10
Introduction
SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. SIGLECs are typically expressed on cells of the innate immune system, with the exception of the B-cell expressed SIGLEC6 (MIM 604405).
Promote the macrophage capability to limit tumour growth
Mycoplasma Testing
Negative
Sterility Testing
Negative
Shipping
Dry ice
Storage
Frozen cells should be stored in a liquid nitrogen tank (-150°C~-190°C) for long term.
Handling Notes
Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance. Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line. Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.