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M2 Macrophage Multicolor Flow Cytometry Panel (MTS-0124-WR1)

Overview

Description
Creative Biolabs provides a flow cytometry panel containing 7 conjugated antibodies targeting different surface and intercellular markers, which can be used for characterizing M2 macrophages.
Applications
The kit is used to characterize M2 macrophages.
Reactivity
Human
Detection Method
Flow cytometry
Method Type
Fluorochrome

Specification

Size
25 tests, 100 tests, 100 μg
Bioassay Target Name
CD3; CD20; CD163; MMR/CD206; NCAM-1/CD56; SR-AI/MSR/CD204; VEGF
Handling Advice
Ensure personal protection by wearing gloves, protective clothing, and eye/face gear. Practice proper hand hygiene after handling.
Storage
Stort at 2-8 °C.
Storage Comment
Upon receipt, please store at the appropriate condition as directed.
Note
For antibody titration, the recommended concentrations are provided as a reference point. Every lab has to find out what works best for their own experiments in terms of concentrations.
Shipping
Ice packs

Target Details

Background
M2 macrophages, also known as tumor-associated macrophages (TAMs), are a subtype of macrophages that are involved in promoting anti-inflammatory responses and inhibiting NK cell cytotoxicity. They express inhibitory ligands and secrete anti-inflammatory cytokines, making them important players in immune regulation. Additionally, M2 macrophages can hinder NK cell function by expressing non-classical MHC I molecules.

For Research Use Only. Do Not Use in Food Manufacturing or Medical Procedures (Diagnostics or Therapeutics). Do Not Use in Humans.

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