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MacroCargo™ Human THP-1 with Chemo drugs (Nanoparticle System, Oligomannose-coated liposome) (MTS-1122-YF235)

Datasheet

Cell Properties

Product Overview

As a therapeutic tool, macrophage cell has a great capacity for delivering cargos because of their intrinsic characteristics. This product is engineered Human THP-1 carried with Chemo drugs by Nanoparticle System-Oligomannose-coated liposome. MacroCargo™ products aim to improve the macrophage function and delivery of specific cargos. We also provide custom macrophage delivery systems based on your specific requirements.

Cell Name

THP-1

Cell Type

Cell Line

Cell Species

Human

Cell Background

THP-1 is a monocyte isolated from peripheral blood from an acute monocytic leukemia patient. This cell line can be used in immune system disorder research, immunology research, and toxicology research.

Cargo Properties

Cargo Type

Chemo drugs

Specific Cargo

Chemo drugs

Introduction

To be determined according to specific requirements

Cargo Delivery System Type

Nanoparticle System

Cargo Delivery Approach

Oligomannose-coated liposome

Nanoparticle Component

DPPC, cholesterol, DPPE, a-methylmannoside, mannotriose.

Product Properties

Applications

Enhance chemotherapeutic drugs delivery to tumor; Reduce side effects

References

Matsui, Makoto et al. "Targeted delivery of oligomannose-coated liposome to the omental micrometastasis by peritoneal macrophages from patients with gastric cancer." Cancer science vol. 101,7 (2010): 1670-7. doi:10.1111/j.1349-7006.2010.01587.x

Mycoplasma Testing

Negative

Sterility Testing

Negative

Shipping

Dry ice

Storage

Frozen cells should be stored in a liquid nitrogen tank (-150°C~-190°C) for long term.

Handling Notes

Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance.
Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line.
Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.

Restriction

Research use only