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MacroCargo™ Mouse Ana-1 with pDNA encoding IL-17b (Nanoparticle System, Magnetic cationic liposomes) (MTS-1222-YF310)

Cell Properties

Product Overview
As a therapeutic tool, macrophage cell has a great capacity for delivering cargos because of their intrinsic characteristics. This product is engineered Mouse Ana-1 carried with pDNA encoding IL-17b by Nanoparticle System-Magnetic cationic liposomes. MacroCargo™ products aim to improve the macrophage function and delivery of specific cargos. We also provide custom macrophage delivery systems based on your specific requirements.
Cell Name
Ana-1
Cell Type
Cell Line
Cell Species
Mouse
Cell Background
Ana-1 is a macrophage cell line, isolated from mouse thymus.

Cargo Properties

Cargo Type
Cytokine
Specific Cargo
pDNA encoding IL-17b
Cargo Common Name
IL17B
Cargo Alternative Names
NIRF; IL-20; IL-17B; ZCYTO7
Cargo Full Name
Interleukin 17B
Introduction
The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies. Alternative splicing results in multiple splice variants.
UniprotID
GeneID
Cargo Delivery System Type
Nanoparticle System
Cargo Delivery Approach
Magnetic cationic liposomes
Nanoparticle Component
DOTAP, DSPC, cholesterol, iron oxide (II, III).

Product Properties

Applications
Improve the delivery of macrophages to tumors and its therapeutic efficacy against inflammatory diseases
Mycoplasma Testing
Negative
Sterility Testing
Negative
Shipping
Dry ice
Storage
Frozen cells should be stored in a liquid nitrogen tank (-150°C~-190°C) for long term.
Handling Notes
Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance.
Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line.
Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.
Restriction
Research use only

For Research Use Only. Do Not Use in Food Manufacturing or Medical Procedures (Diagnostics or Therapeutics). Do Not Use in Humans.

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