The ready-to-use SIGLEC10 gRNA Lentiviral Particle is packaged using 3rd generation of lentiviral packaging system, which is a research tool for macrophage cell engineering in vivo and in vitro.
Product Type
Virus Particles
Application Scenario
For in vivo and in vitro macrophage engineering
Target Specification
Engineering Approach
Target KO gRNA Contruction Lentivirus
Species
Human
Target
SIGLEC10 gRNA
Alternative Names
SLG2; PRO940; SIGLEC-10
Full Name
Sialic acid binding Ig like lectin 10
Introduction
SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. SIGLECs are typically expressed on cells of the innate immune system, with the exception of the B-cell expressed SIGLEC6 (MIM 604405).