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MacroCargo™ Mouse Bone Marrow-derived Macrophages (BMDM) with Anti-LAG3 antibody (Viral System, Lentivirus) (MTS-1122-YF74)

Datasheet

Cell Properties

Product Overview

As a therapeutic tool, macrophage cell has a great capacity for delivering cargos because of their intrinsic characteristics. This product is engineered Mouse Bone Marrow-derived Macrophages (BMDM) carried with Anti-LAG3 antibody by Viral System-Lentivirus. MacroCargo™ products aim to improve the macrophage function and delivery of specific cargos. We also provide custom macrophage delivery systems based on your specific requirements.

Cell Name

Bone Marrow-derived Macrophages (BMDM)

Cell Type

Primary Cell

Cell Species

Mouse

Cell Background

The broad use of transgenic and gene-targeted mice has established bone marrow-derived macrophages (BMDM) as important mammalian host cells for investigation of the macrophages biology.

Cargo Properties

Cargo Type

Checkpoint antibody

Specific Cargo

Anti-LAG3 antibody

Target Common Name

LAG3

Target Alternative Names

CD223

Target Full Name

lymphocyte activating 3

Introduction

Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4.

UniprotID

P18627

GeneID

3902

Cargo Delivery System Type

Viral System

Cargo Delivery Approach

Lentivirus

Product Properties

Applications

Resistant to reprogramming by tumor-secreted signals

Mycoplasma Testing

Negative

Sterility Testing

Negative

Shipping

Dry ice

Storage

Frozen cells should be stored in a liquid nitrogen tank (-150°C~-190°C) for long term.

Handling Notes

Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance.
Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line.
Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.

Restriction

Research use only