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IFN-γ Lentiviral Particle for Macrophage Engineering (MTS-0124-LX6)

Datasheet

Overview

Description

IFN-γ is involved in serveral macrophage related functions, including as the positive regulator of M1 polarization of macrophage; improving survive. The ready-to-use IFN-γ Lentiviral Particle is packaged using 3rd generation of lentiviral packaging system, which is a research tool for macrophage cell engineering in vivo and in vitro.

Product Type

Virus Particles

Application Scenario

For in vivo and in vitro macrophage engineering

Target Specification

Engineering Approach

Cytokine Gene Overexpression-Lentivirus

Species

Human

Target

IFN-γ

Alternative Names

IFG; IFI; IMD69

Full Name

Interferon gamma

Introduction

This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases.

UniprotID

P01579

GeneID

3458

Applications

Positive regulator of M1 polarization of macrophage; Improve survival

Product Specification

Packaging System

Lentivirus

Titer

>1E8 TU/mL

Size

200uL; 1mL

Mycoplasma Testing

Negative

Sterility Testing

Negative

Shipping

Dry ice

Storage

Stored at -80°C for long term.

Handling Notes

Avoid multiple freeze/thaw cycles.

Restriction

RUO

For Research Use Only. Do Not Use in Food Manufacturing or Medical Procedures (Diagnostics or Therapeutics). Do Not Use in Humans.