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MacroCargo™ Human PBMC-derived Macrophages with Nanoparticle System, PEGylated gold-based nanoparticles (MTS-1222-YF510)

Cell Properties

Product Overview
As a therapeutic tool, macrophage cell has a great capacity for delivering cargos because of their intrinsic characteristics. This product is engineered Human PBMC-derived Macrophages carried with Nanoparticle System-PEGylated gold-based nanoparticles. MacroCargo™ products aim to improve the macrophage function and delivery of specific cargos. We also provide custom macrophage delivery systems based on your specific requirements.
Cell Name
PBMC-derived Macrophages
Cell Type
Primary Cell
Cell Species
Human
Cell Background
Macrophages are specialised cells involved in the detection, phagocytosis and destruction of bacteria and other harmful organisms. In addition, they can also present antigens to T cells and initiate inflammation by releasing molecules (known as cytokines) that activate other cells. Furthermore, macrophages are able to cross the biological barriers, penetrate into tumors, and accumulate particularly in hypoxic and poorly vascularized portions of a tumor.

Cargo Properties

Cargo Delivery System Type
Nanoparticle System
Cargo Delivery Approach
PEGylated gold-based nanoparticles
Nanoparticle Component
Silica core with gold shell

Product Properties

Applications
Photothermal therapy
References
Madsen, Steen J et al. "Nanoparticle-loaded macrophage-mediated photothermal therapy: potential for glioma treatment." Lasers in medical science vol. 30,4 (2015): 1357-65. doi:10.1007/s10103-015-1742-5
Mycoplasma Testing
Negative
Sterility Testing
Negative
Shipping
Dry ice
Storage
Frozen cells should be stored in a liquid nitrogen tank (-150°C~-190°C) for long term.
Handling Notes
Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance.
Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line.
Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.
Restriction
Research use only

For Research Use Only. Do Not Use in Food Manufacturing or Medical Procedures (Diagnostics or Therapeutics). Do Not Use in Humans.

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