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GITR-L gRNA Lentiviral Particle for Macrophage Engineering (MTS-0124-LX23)

Datasheet

Overview

Description

GITR-L participated in TMA related functions, such as inducing anti-tumor macrophage phenotypes. The ready-to-use GITR-L gRNA Lentiviral Particle is packaged using 3rd generation of lentiviral packaging system, aiding in the research of macrophage cell engineering.

Product Type

Virus Particles

Application Scenario

For in vivo and in vitro macrophage engineering

Target Specification

Engineering Approach

Target KO gRNA Contruction Lentivirus

Species

Human

Target

GITR-L gRNA

Alternative Names

TL6; AITRL; GITRL; TNLG2A; hGITRL

Full Name

TNF superfamily member 18

UniprotID

Q9UNG2

GeneID

8995

Applications

Induce anti-tumor macrophage phenotypes

Reference

Brom, Victoria C et al. "The Role of Immune Checkpoint Molecules on Macrophages in Cancer, Infection, and Autoimmune Pathologies." Frontiers in immunology vol. 13 837645. 28 Mar. 2022, doi:10.3389/fimmu.2022.837645

Product Specification

Packaging System

Lentivirus

Titer

>1E8 TU/mL

Size

200uL; 1mL

Mycoplasma Testing

Negative

Sterility Testing

Negative

Shipping

Dry ice

Storage

Stored at -80°C for long term.

Handling Notes

Avoid multiple freeze/thaw cycles.

Restriction

RUO

For Research Use Only. Do Not Use in Food Manufacturing or Medical Procedures (Diagnostics or Therapeutics). Do Not Use in Humans.