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FPN1 shRNA Lentiviral Particle for Macrophage Engineering (MTS-0124-LX16)

Datasheet

Overview

Description
SLC40A1 as a key iron metabolism-related gene in airway macrophages. The pre-made FPN1 shRNA Lentiviral Particle is a research tool to aid in macrophage cell engineering.
Product Type
Virus Particles
Application Scenario
For in vivo and in vitro macrophage engineering

Target Specification

Engineering Approach
Target shRNA Lentivirus
Species
Human
Target
FPN1
Alternative Names
FPN; FPN1; HFE4; MTP1; IREG1; MST079; MSTP079; SLC11A3
Full Name
Solute carrier family 40 member 1
Introduction
The protein encoded by this gene is a cell membrane protein that may be involved in iron export from duodenal epithelial cells. Defects in this gene are a cause of hemochromatosis type 4 (HFE4).
UniprotID
Q9NP59
GeneID
30061
Applications
Induce macrophage polarization into the M1 phenotype; Inhibits tumor growth

Product Specification

Packaging System
Lentivirus
Titer
>1E8 TU/mL
Size
200uL; 1mL
Mycoplasma Testing
Negative
Sterility Testing
Negative
Shipping
Dry ice
Storage
Stored at -80°C for long term.
Handling Notes
Avoid multiple freeze/thaw cycles.
Restriction
RUO

For Research Use Only. Do Not Use in Food Manufacturing or Medical Procedures (Diagnostics or Therapeutics). Do Not Use in Humans.

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