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MacroCargo™ Rat Alveolar Macrophages with Anti-LAG3 antibody (Viral System, Lentivirus) (MTS-1122-YF260)

Datasheet

Cell Properties

Product Overview

As a therapeutic tool, macrophage cell has a great capacity for delivering cargos because of their intrinsic characteristics. This product is engineered Rat Alveolar Macrophages carried with Anti-LAG3 antibody by Viral System-Lentivirus. MacroCargo™ products aim to improve the macrophage function and delivery of specific cargos. We also provide custom macrophage delivery systems based on your specific requirements.

Cell Name

Rat Alveolar Macrophages

Cell Type

Primary Cell

Cell Species

Rat

Cell Background

Alveolar macrophages (AM) are important in the regulation of immune responses in the lung, through their role as scavenger cells and through the production of many bioactive factors.

Cargo Properties

Cargo Type

Checkpoint antibody

Specific Cargo

Anti-LAG3 antibody

Target Common Name

LAG3

Target Alternative Names

CD223

Target Full Name

lymphocyte activating 3

Introduction

Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4.

UniprotID

P18627

GeneID

3902

Cargo Delivery System Type

Viral System

Cargo Delivery Approach

Lentivirus

Product Properties

Applications

Resistant to reprogramming by tumor-secreted signals

Mycoplasma Testing

Negative

Sterility Testing

Negative

Shipping

Dry ice

Storage

Frozen cells should be stored in a liquid nitrogen tank (-150°C~-190°C) for long term.

Handling Notes

Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance.
Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line.
Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.

Restriction

Research use only