Online Inquiry

Kupffer Cells, Liver Macrophages (MT-0224-HM10)

Datasheet

Overview

Description

Kupffer cells are a type of specialized macrophage primarily found in the liver. They constitute the largest population of tissue-resident macrophages in the body.

Applications

Numerous types of experimental manipulations, including morphological, gene expression, and physiological studies.

Species

Mouse

Original

Erythro-myeloid Progenitors

Product Type

Tissue-specific Macrophages

Specification

Cell Source

Liver

Status

Frozen

Formulation

Cryopreservation medium

Quality Control

Cells are negative for mycoplasma, bacteria, fungi and yeast.

Medium

Recommended medium

Shipping Info

Dry ice

Size

1×10⁶ cells

Handling Notes

Upon receiving, transfer this product directly from dry ice to liquid nitrogen(-150°C~-190°C) and store it in a liquid nitrogen tank.
We cannot guarantee the cell viability if the cells are not treated appropriately according to handling procedure.

Storage

Avoid repeated freezing & thawing.

Product Disclaimer

Product Disclaimer

This product is provided for research only, not suitable for human or animal use.
We ensure the safety of our products, but we still recommend handling any biological materials with standard precautions as if able to spread infectious disease.

FAQs Customer Reviews Related Products

Are these Kupffer cells suitable for modeling inflammation during drug-induced liver injury?

Yes. Their robust reaction to inflammatory stimuli enables detailed mapping of toxicant-triggered cytokine cascades. They are ideal for screening drug candidates, analyzing immune-mediated liver stress, and evaluating metabolic interactions.

Can these cells be used alongside hepatocytes or stellate cells in co-culture?

Absolutely. Kupffer cells naturally interact with multiple hepatic lineages. Their stable integrative behavior allows realistic modeling of inflammation, fibrosis, or hepatocyte-macrophage communication.

How do you maintain high post-thaw viability in cryopreserved Kupffer cells?

They are preserved in optimized cryomedium supporting membrane integrity and phagocytic functions. Post-thaw QC confirms viability and responsiveness, ensuring readiness for immediate experimental workflows.

These Kupffer cells displayed robust phagocytic and inflammatory behaviors, making them ideal for hepatotoxicity profiling
Their cytokine responses to LPS and metabolic stressors were clean, reproducible, and aligned with in vivo expectations.
The cells attached quickly after thawing and remained functionally stable for several days
It allowed us to perform repeated-dose toxicity studies with consistent results.
A dependable product for liver immunology work
We observed very consistent behavior across batches, which significantly reduced the variability in our early-stage screening assays.

For Research Use Only. Do Not Use in Food Manufacturing or Medical Procedures (Diagnostics or Therapeutics). Do Not Use in Humans.