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Anti-LAG3 antibody Lentiviral Particle for Macrophage Engineering (MTS-0124-LX18)

Datasheet

Overview

Description

LAG3 showed negative impact in serveral macrophage related functions, including showing resistence to reprogramming by tumor-secreted signals. The ready-to-use Anti-LAG3 antibody Lentiviral Particle is packaged using 3rd generation of lentiviral packaging system, which is a research tool for macrophage cell engineering in vivo and in vitro.

Product Type

Virus Particles

Application Scenario

For in vivo and in vitro macrophage engineering

Target Specification

Engineering Approach

Checkpoint Antibody Seq Overexpression-Lentivirus

Species

Human

Target

Anti-LAG3 antibody

Alternative Names

CD223

Full Name

lymphocyte activating 3

Introduction

Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4.

UniprotID

P18627

GeneID

3902

Applications

Resistant to reprogramming by tumor-secreted signals

Product Specification

Packaging System

Lentivirus

Titer

>1E8 TU/mL

Size

200uL; 1mL

Mycoplasma Testing

Negative

Sterility Testing

Negative

Shipping

Dry ice

Storage

Stored at -80°C for long term.

Handling Notes

Avoid multiple freeze/thaw cycles.

Restriction

RUO

For Research Use Only. Do Not Use in Food Manufacturing or Medical Procedures (Diagnostics or Therapeutics). Do Not Use in Humans.